FOX04-DRI 10mg (Proxofim)

$250.00

Researched Benefits:

  • Facilitates analysis of FOXO4-p53 interaction inhibition for investigating targeted senolysis
  • Supports investigation into p53-mediated mitochondrial apoptosis in senescent cell assays
  • Enables research on selective elimination of senescent fibroblasts and myofibroblasts
  • Useful for evaluating homeostatic recovery and cellular rejuvenation in aging-related models

Description

FOXO4-DRI 10 mg (Proxofim) is a synthetic D-retro-inverso peptide engineered to disrupt the FOXO4-p53 interaction that allows senescent cells to resist apoptosis. By reinstating p53-mediated cell death in these cells, FOXO4-DRI functions as a potent senolytic agent in pre-clinical studies, opening new avenues for research into age-related degeneration and chronic inflammatory conditions.

Key Features:

  • Manufactured under stringent cGMP-like conditions to ensure ≥99 % purity and batch-to-batch consistency.

  • Lyophilized powder for maximum stability; reconstitutes rapidly in sterile distilled water or buffer.

  • Extensively validated by HPLC and mass spectrometry for precise molecular integrity.

Applications:

  • Investigating senolytic mechanisms and selective clearance of senescent cells.

  • Exploring therapeutic potential in age-associated tissue dysfunction and metabolic decline.

  • Assessing downstream effects on oxidative stress, insulin signaling, and cancer cell plasticity.

Specifications and Documentation

  • Material Safety Data Sheet (MSDS): Coming Soon.

  • Handling and Storage Instructions: Coming Soon.

FOXO4-DRI has emerged as a valuable research tool for probing cellular senescence, regenerative biology, and longevity science, offering investigators a robust platform for advancing anti-aging and disease-modifying strategies.

Additional information

CAS No. 2460055-10-9
Purity ≥99%
Sequence D-(Leu-Thr-Leu-Arg-Lys-Glu-Pro-Ala-Ser-Glu-Ile-Ala-Gln-Ser-Ile-Leu-Glu-Ala-Tyr-Ser-Gln-Asn-Gly-Trp-Ala-Asn-Arg-Arg-Ser-Gly-Gly-Lys-Arg-Pro-Pro-Pro-Arg-Arg-Arg-Gln-Arg-Arg-Lys-Lys-Arg-Gly)
Molecular Formula C₂₂₈H₃₈₈N₈₆O₆₄
Molecular Weight 358.06 g/mol
Applications Senescence research, anti-aging studies, degenerative disease models
Synthesis Solid-phase synthesis
Solubility Soluble in water or 1% acetic acid
Stability & Storage Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months.
Appearance White lyophilized powder
Shipping Conditions Shipped at ambient temperature; once received, store at -20°C
Regulatory/Compliance Manufactured in a facility that adheres to cGMP guidelines
Safety Information Refer to provided MSDS

Description

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FOX04-DRI is a synthetic peptide analog studied in experimental peptide science. Researchers examine this compound in laboratory models to better understand its interaction with molecular signaling pathways and peptide-mediated regulatory mechanisms.

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Research Applications

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Product Specifications

Pure Peptide Labs FOX04-DRI is manufactured with strict laboratory quality control standards to ensure consistency and reliability for research purposes.

Key specifications include:

  • Purity: ≥98% research grade
  • Form: Lyophilized peptide powder
  • Storage: Refrigerate at 2–8°C
  • Intended Use: Laboratory research only

Each production batch undergoes analytical testing to verify purity and stability. Buy FOX04-DRI Peptide


FOX04-DRI Product Details

Feature Details
Product Name FOX04-DRI
Category Research Peptide
Purity ≥98%
Form Lyophilized Powder
Brand Pure Peptide Labs
Intended Use Laboratory Research Only

Laboratory Handling Guidelines

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  • Store the peptide under refrigeration
  • Avoid contamination during preparation
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Frequently Asked Questions

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Related Research Peptides

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