PNC-27 30mg

$200.00

Researched Benefits:

  • Facilitates analysis of p53-derived peptide binding to the HDM2-receptor signaling complex
  • Supports investigation into membrane-permeabilization mechanisms within p53-deficient cellular assay models
  • Enables research on HDM2-mediated E3 ubiquitin ligase inhibition and proteasomal degradation
  • Useful for evaluating selective peptide-induced necrosis through specific trans-membrane helical interactions

Description

PNC-27 30mg is a chimeric research peptide explored for its potent, selective cytotoxicity against malignant cells. Engineered from the HDM-2-binding domain of p53 fused to a cell-penetrating leader sequence, PNC-27 disrupts tumor-cell membranes while leaving healthy cells largely unharmed. Synthesized from premium raw materials and rigorously purified, our PNC-27 offers exceptional consistency and reliability for advanced oncological investigations.

Key Features:

  • Manufactured under stringent GMP-compliant conditions to maximize purity and bioactivity.

  • Each lot is subjected to comprehensive HPLC and mass-spectrometry analysis for quality assurance.

  • Supplied as a lyophilized powder to preserve structural integrity during storage and transport.

Applications:

  • Elucidating mechanisms of HDM-2 interaction and membrane pore formation in tumor cells.

  • Assessing selective cytotoxicity and necrosis induction across diverse cancer lines.

  • Investigating synergistic potential with existing chemotherapeutic agents.

Specifications and Documentation

  • Material Safety Data Sheet (MSDS): Coming Soon.

  • Handling and Storage Instructions: Coming Soon.

PNC-27 30mg provides researchers with a precise tool to interrogate targeted anti-cancer strategies, paving the way for deeper insights into tumor-selective therapies.

Additional information

CAS No. 1159861-00-3
Purity ≥99%
Sequence Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly
Molecular Formula C188H293N53O44S
Molecular Weight 4031.73 g/mol
Applications Oncology studies, tumor necrosis assays, HDM-2 binding research, selective anti-cancer mechanisms
Synthesis Solid-phase synthesis
Solubility Soluble in water or 1% acetic acid
Stability & Storage Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months.
Appearance White lyophilized powder
Shipping Conditions Shipped at ambient temperature; once received, store at -20°C
Regulatory/Compliance Manufactured in a facility that adheres to cGMP guidelines
Safety Information Refer to provided MSDS

Description

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PNC-27 is a synthetic peptide studied in experimental research environments for its interactions with cellular pathways and peptide-mediated molecular mechanisms. Researchers investigate PNC-27 in laboratory models to better understand peptide signaling and biological regulatory processes.

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Research Applications

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Product Specifications

Pure Peptide Labs PNC-27 is produced under strict laboratory quality control procedures to ensure consistent purity and reliability. Buy PNC-27 Peptide

Key specifications include:

  • Purity: ≥98% research grade
  • Form: Lyophilized peptide powder
  • Storage: Refrigerate at 2–8°C
  • Intended Use: Laboratory research only

Each batch undergoes analytical testing to confirm purity and stability. Buy PNC-27 Peptide


PNC-27 Product Details

Feature Details
Product Name PNC-27
Category Research Peptide
Purity ≥98%
Form Lyophilized Powder
Brand Pure Peptide Labs
Intended Use Laboratory Research Only

Laboratory Handling Guidelines

To ensure peptide stability and accurate experimental results:

  • Use sterile laboratory equipment when preparing solutions
  • Store PNC-27 under recommended refrigeration conditions
  • Avoid contamination during peptide handling
  • Follow established laboratory peptide handling protocols

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Quality Assurance

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Shipping & Delivery

Pure Peptide Labs offers worldwide shipping for PNC-27. Orders are carefully packaged to preserve peptide stability and ensure safe delivery to laboratories and research institutions. Buy PNC-27 Peptide


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Frequently Asked Questions

Is PNC-27 intended for human consumption?
No. PNC-27 is strictly intended for laboratory research purposes only.

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Related Research Peptides

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